KIR2DS2 抗体
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- 抗原 See all KIR2DS2 抗体
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIR2DS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human KIR2DS2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product KIR2DS2 Primary Antibody
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anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 104-241) antibody
KIR2DS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 22-304) antibodyKIR2DS2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2) (AA 39-65) antibodyKIR2DS2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26424 unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Jurkat
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
- 别名
- KIR2DS2 (KIR2DS2 产品)
- 别名
- 183ActI antibody, CD158J antibody, CD158b antibody, NKAT5 antibody, cl-49 antibody, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antibody, KIR2DS2 antibody
- 背景
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Synonyms: killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 , 183ActI , CD158J , CD158b , KIR-2DS2 , NKAT-5 , NKAT5 , cl-49
Background: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq]
- 分子量
- 34 kDa
- 基因ID
- 100132285
- UniProt
- P43631
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