GIT2 抗体
Quick Overview for GIT2 抗体 (ABIN7469377)
抗原
See all GIT2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human GIT2. The exact sequence is proprietary.
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亚型
- IgG
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anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibody
GIT2 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal M1 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B5-B9 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-603) antibodyGIT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (Internal Region) antibodyGIT2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-471) antibodyGIT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 401-498) antibodyGIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 714-749), (C-Term) antibodyGIT2 适用: 人 WB 宿主: 兔 Polyclonal RB48356 unconjugated
anti-G Protein-Coupled Receptor Kinase Interactor 2 (GIT2) (AA 1-312) antibodyGIT2 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , mouse liver
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.81 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
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别名
- GIT2
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背景
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Synonyms: GIT ArfGAP 2 , CAT-2 , CAT2 , PKL
Background: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq]
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分子量
- 85 kDa
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基因ID
- 9815
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UniProt
- Q14161
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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