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ELAC2 抗体

This anti-ELAC2 antibody is a 兔 多克隆 antibody detecting ELAC2 in WB, IP 和 IHC (p). Suitable for 人.
产品编号 ABIN7469339
发货至: 中国

Quick Overview for ELAC2 抗体 (ABIN7469339)

抗原

See all ELAC2 抗体
ELAC2 (ElaC Homolog 2 (ELAC2))

适用

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宿主

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克隆类型

  • 35
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多克隆

标记

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This ELAC2 antibody is un-conjugated

应用范围

  • 13
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ELAC2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Jurkat , Raji , NCI-H929

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.73 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ELAC2 (ElaC Homolog 2 (ELAC2))

    别名

    ELAC2

    背景

    Synonyms: elaC ribonuclease Z 2 , COXPD17 , ELC2 , HPC2

    Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    分子量

    92 kDa

    基因ID

    60528

    UniProt

    Q9BQ52
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