GATSL3 抗体
Quick Overview for GATSL3 抗体 (ABIN7469300)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
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亚型
- IgG
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anti-GATS Protein-Like 3 (GATSL3) (C-Term) antibody
GATSL3 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MCF-7 , MDA-MB-231
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.9 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GATSL3 (GATS Protein-Like 3 (GATSL3))
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别名
- GATSL3
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背景
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Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3
Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
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分子量
- 36 kDa
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基因ID
- 652968
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UniProt
- Q8WTX7
抗原
-
