COX10 抗体
Quick Overview for COX10 抗体 (ABIN7469298)
抗原
See all COX10 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human COX10. The exact sequence is proprietary.
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亚型
- IgG
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anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 383-410), (C-Term) antibody
COX10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24307 unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (Middle Region) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 386-414), (C-Term) antibodyCOX10 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) antibodyCOX10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 215-264) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 180-229) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-160) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , SK-N-SH , IMR-32 , SK-N-AS
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
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别名
- COX10
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背景
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Synonyms: cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq]
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分子量
- 49 kDa
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基因ID
- 1352
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UniProt
- Q12887
抗原
-
