MBD5 抗体
Quick Overview for MBD5 抗体 (ABIN7469295)
抗原
See all MBD5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MBD5. The exact sequence is proprietary.
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亚型
- IgG
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anti-Methyl-CpG Binding Domain Protein 5 (MBD5) (AA 1-229) antibody
MBD5 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4A12-1B6 unconjugated
anti-Methyl-CpG Binding Domain Protein 5 (MBD5) (AA 1-229) antibodyMBD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 5 (MBD5) (AA 1-229) antibodyMBD5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2 nuclear extract Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.19 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))
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别名
- MBD5
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背景
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Synonyms: methyl-CpG binding domain protein 5 , MRD1
Background: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq]
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分子量
- 160 kDa
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基因ID
- 55777
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UniProt
- Q9P267
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途径
- Chromatin Binding
抗原
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