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Acetyl-CoA Carboxylase alpha 抗体 (C-Term)

This 兔 多克隆 anti-Acetyl-CoA Carboxylase alpha antibody specifically detects Acetyl-CoA Carboxylase alpha in WB, IHC (p), IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7469285
发货至: 中国
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Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (C-Term) (ABIN7469285)

抗原

See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
Acetyl-CoA Carboxylase alpha (ACACA)

适用

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宿主

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克隆类型

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多克隆

标记

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This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human Acetyl-CoA Carboxylase 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.55 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Acetyl-CoA Carboxylase alpha (ACACA)

    别名

    Acetyl-CoA Carboxylase 1

    背景

    Synonyms: acetyl-CoA carboxylase alpha , ACAC , ACACAD , ACC , ACC1 , ACCA

    Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    分子量

    266 kDa

    基因ID

    31

    UniProt

    Q13085

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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