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BCR 抗体 (C-Term)

Name: BCR 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN7469259
Availability: OutOfStock

This anti-BCR antibody is a 兔多克隆 antibody detecting BCR in WB 和 IHC (p). Suitable for 人.

产品编号 ABIN7469259

发货至: 中国

Datasheet as PDF

Quick Overview for BCR 抗体 (C-Term) (ABIN7469259)

抗原

See all BCR 抗体

BCR (Breakpoint Cluster Region (BCR))

适用

人

宿主

兔

克隆类型

多克隆

标记

This BCR antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

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抗原表位
30

16

8

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

交叉反应

人

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human Bcr. The exact sequence is proprietary.

亚型

IgG
anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E5 unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 139-280) antibody
BCR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E11G12 unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibody
BCR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibody
BCR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (N-Term) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibody
BCR 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr177) antibody
BCR 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Breakpoint Cluster Region (BCR) (pTyr360) antibody
BCR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: Molt-4

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

BCR (Breakpoint Cluster Region (BCR))

别名

BCR

背景

Synonyms: BCR activator of RhoGEF and GTPase , ALL , BCR1 , CML , D22S11 , D22S662 , PHL
Background: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

分子量

143 kDa

基因ID

613

UniProt

P11274

途径

Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling