BCL10 抗体
Quick Overview for BCL10 抗体 (ABIN7469258)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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特异性
- IP/MS validation was supported by references (PMID:30377407)
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human BCL10. The exact sequence is proprietary.
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亚型
- IgG
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anti-B-Cell CLL/lymphoma 10 (BCL10) antibody
BCL10 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 IHC, IF, FACS, StM 宿主: 兔 Monoclonal BL10-2988R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BL10-411 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 98-234) antibodyBCL10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3C11F4 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-143) antibodyBCL10 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1185CT13-2-1-2 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 24-51), (N-Term) antibodyBCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24271 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4F8 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Raji , Neuro2A , GL261 , C8D30 , HeLa Validation: IP/MS, KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- BCL10
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背景
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Synonyms: BCL10 immune signaling adaptor , CARMEN , CIPER , CLAP , IMD37 , c-E10 , mE10
Background: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq]
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分子量
- 26 kDa
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基因ID
- 8915
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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