Uncoupling Protein 1 抗体
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北京 101111
Quick Overview for Uncoupling Protein 1 抗体 (ABIN7469138)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鼠
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纯化方法
- Affinity purified by Protein G.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human UCP1. The exact sequence is proprietary.
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亚型
- IgG1
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: mouse brown adipose
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Uncoupling Protein 1
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背景
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Synonyms: uncoupling protein 1 , SLC25A7 , UCP
Background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
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分子量
- 33 kDa
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基因ID
- 7350
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UniProt
- P25874
抗原
-
