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TSG101 抗体

This anti-TSG101 antibody is a 兔 多克隆 antibody detecting TSG101 in WB, ELISA, IP 和 IHC (p). Suitable for 人.
产品编号 ABIN7469108
发货至: 中国

Quick Overview for TSG101 抗体 (ABIN7469108)

抗原

See all TSG101 抗体
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

适用

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宿主

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克隆类型

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多克隆

标记

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This TSG101 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TSG101. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , U87-MG , SK-N-SH , IMR32 , SK-N-AS Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.09 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    别名

    tumor susceptibility 101

    背景

    Synonyms: tumor susceptibility 101 , TSG10 , VPS23

    Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq]

    分子量

    44 kDa

    基因ID

    7251

    UniProt

    Q99816
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