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TSG101 抗体 (AA 167-374)

This anti-TSG101 antibody is a 小鼠 单克隆 antibody detecting TSG101 in WB, IHC, ELISA, IP, IF, IHC (p), FACS, ICC, IEM 和 IHC (ff). Suitable for 人.
产品编号 ABIN7469107
发货至: 中国

Quick Overview for TSG101 抗体 (AA 167-374) (ABIN7469107)

抗原

See all TSG101 抗体
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TSG101 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM), Immunohistochemistry (Free Floating) (IHC (ff))

质量等级

KO Validated

克隆位点

4A10
  • 抗原表位

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    AA 167-374

    特异性

    Knockdown/Knockout validation was supported by references (PMID:27226592)

    交叉反应

    犬, Hamster, 人, 猴, 小鼠, Pig, 大鼠, 斑马鱼

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Amino acids 167-374 of TSG101 protein expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:500-1:1000. IHC-P: 1:100-1:1000. FACS: 1:25-1:200. EM: 1:10. IHC: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , K562 , THP-1 , HL-60 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , NIH-3T3 , JC , BCL-1 Validation: KO/KD, Orthogonal, Overexpression, Recombinant antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.8 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    别名

    tumor susceptibility 101

    背景

    Synonyms: tumor susceptibility 101 , TSG10 , VPS23

    Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]

    分子量

    44 kDa

    基因ID

    7251

    UniProt

    Q99816
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