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TNNT1 抗体

This anti-TNNT1 antibody is a 兔 多克隆 antibody detecting TNNT1 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7468979
发货至: 中国

Quick Overview for TNNT1 抗体 (ABIN7468979)

抗原

See all TNNT1 抗体
TNNT1 (Slow Skeletal Troponin T (TNNT1))

适用

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宿主

  • 24
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克隆类型

  • 27
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多克隆

标记

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This TNNT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, Pig

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Full length human Troponin T1 (slow) skeletal muscle Recombinant protein.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: H1299

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.89 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TNNT1 (Slow Skeletal Troponin T (TNNT1))

    别名

    troponin T1, slow skeletal type

    背景

    Synonyms: troponin T1, slow skeletal type , ANM , NEM5 , STNT , TNT , TNTS

    Background: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    分子量

    33 kDa

    基因ID

    7138

    UniProt

    P13805
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