SLIT2 抗体
Quick Overview for SLIT2 抗体 (ABIN7468977)
抗原
See all SLIT2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SLIT2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody
SLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 664-777) antibodySLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) antibodySLIT2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1160-1333) antibodySLIT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) antibodySLIT2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 451-550) antibodySLIT2 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1361-1460) antibodySLIT2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody (Biotin)SLIT2 适用: 人 WB 宿主: 兔 Polyclonal Biotin
anti-Slit Homolog 2 (Drosophila) (SLIT2) (AA 1416-1528) antibody (FITC)SLIT2 适用: 人 WB 宿主: 兔 Polyclonal FITC
anti-Slit Homolog 2 (Drosophila) (SLIT2) (Internal Region) antibodySLIT2 适用: 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:10000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: IMR32 , SK-N-AS , mouse brain , rat brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.17 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
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别名
- slit guidance ligand 2
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背景
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Synonyms: slit guidance ligand 2 , SLIL3 , Slit-2
Background: Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.
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分子量
- 170 kDa
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基因ID
- 9353
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UniProt
- O94813
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途径
- Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
抗原
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