Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) 抗体
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Quick Overview for Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) 抗体 (ABIN7468819)
抗原
适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Park7 / DJ-1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Protein/nucleic Acid Deglycase DJ-1 (PARK7) antibody
KD Validated PARK7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1955 unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Protein/nucleic Acid Deglycase DJ-1 (PARK7)
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别名
- Parkinsonism associated deglycase
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背景
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Synonyms: Parkinsonism associated deglycase , DJ-1 , DJ1 , GATD2 , HEL-S-67p
Background: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
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分子量
- 20 kDa
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基因ID
- 11315
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UniProt
- Q99497
抗原
-
