PMS2CL/PMS2 抗体 (N-Term)
This 兔 多克隆 antibody specifically detects PMS2CL/PMS2 in IP 和 WB. It exhibits reactivity toward 人.
产品编号 ABIN7468755
发货至:
中国
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Quick Overview for PMS2CL/PMS2 抗体 (N-Term) (ABIN7468755)
抗原
PMS2CL/PMS2 (PMS2)
(PMS1 Homolog 2, Mismatch Repair System Component (PMS2))
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Immunoprecipitation (IP), Western Blotting (WB)
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抗原表位
- N-Term
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human PMS2. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: human PMS2-transfected 293T cells , A431 , HeLa , HepG2 Validation: Overexpression
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PMS2CL/PMS2 (PMS2) (PMS1 Homolog 2, Mismatch Repair System Component (PMS2))
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别名
- PMS1 homolog 2, mismatch repair system component
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背景
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Synonyms: PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2
Background: This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
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分子量
- 96 kDa
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基因ID
- 5395
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UniProt
- P54278
抗原
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