KMT5A 抗体
This anti-KMT5A antibody is a 兔 多克隆 antibody detecting KMT5A in ICC, IF, IHC (p) 和 WB. Suitable for 人.
Quick Overview for KMT5A 抗体 (ABIN7468629)
抗原
KMT5A
(N-Lysine Methyltransferase KMT5A (KMT5A))
适用
人
宿主
兔
克隆类型
多克隆
标记
This KMT5A antibody is un-conjugated
应用范围
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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交叉反应
- C. elegans, 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SETD8. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- KMT5A (N-Lysine Methyltransferase KMT5A (KMT5A))
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别名
- lysine methyltransferase 5A
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背景
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Synonyms: lysine methyltransferase 5A , PR-Set7 , PR/SET07 , SET07 , SET8 , SETD8
Background: Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
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分子量
- 43 kDa
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基因ID
- 387893
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UniProt
- Q9NQR1
抗原
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