LIN7A 抗体
Quick Overview for LIN7A 抗体 (ABIN7468550)
抗原
See all LIN7A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Affinity purified by Protein G.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human LIN7A. The exact sequence is proprietary.
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亚型
- IgG1
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anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibody
LIN7A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibodyLIN7A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-90) antibodyLIN7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MCF-7 , MDA-MB-231
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- LIN7A (Lin-7 Homolog A (LIN7A))
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别名
- lin-7 homolog A, crumbs cell polarity complex component
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背景
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Synonyms: lin-7 homolog A, crumbs cell polarity complex component , LIN-7A , LIN7 , MALS-1 , MALS1 , TIP-33 , VELI1
Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
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分子量
- 26 kDa
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基因ID
- 8825
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UniProt
- O14910
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途径
- Synaptic Membrane
抗原
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