KAT2A 抗体 (C-Term)
Quick Overview for KAT2A 抗体 (C-Term) (ABIN7468506)
抗原
See all KAT2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody was raised against KAT2A protein, and based on sequence homology, it may cross react with KAT2B protein.
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human GCN5. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: NIH-3T3 , JC , BCL-1 Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))
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别名
- lysine acetyltransferase 2A
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背景
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Synonyms: lysine acetyltransferase 2A , GCN5 , GCN5L2 , PCAF-b , hGCN5
Background: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM]
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分子量
- 94 kDa
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基因ID
- 2648
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UniProt
- Q92830
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途径
- Chromatin Binding, Tube Formation
抗原
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