ITGAL 抗体
Quick Overview for ITGAL 抗体 (ABIN7468487)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 小鼠
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纯化方法
- Affinity purified by Protein G.
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免疫原
- The immunogen used to generate this antibody corresponds to human CD11a
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亚型
- IgG2a
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应用备注
- FACS: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- integrin subunit alpha L
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背景
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Synonyms: integrin subunit alpha L , CD11A , LFA-1 , LFA1A
Background: ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
- 129 kDa
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基因ID
- 3683
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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