ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1) (C-Term) 抗体
The 兔 多克隆 anti-ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 antibody is suitable to detect ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 in samples from 人. It has been validated for WB.
产品编号 ABIN7468312
发货至:
中国
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Quick Overview for ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1) (C-Term) 抗体 (ABIN7468312)
抗原
ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1)
适用
人
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
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抗原表位
- C-Term
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human EDEM1. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat membrane extract Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.21 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1)
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别名
- ER degradation enhancing alpha-mannosidase like protein 1
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背景
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Synonyms: ER degradation enhancing alpha-mannosidase like protein 1 , EDEM
Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.
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分子量
- 74 kDa
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基因ID
- 9695
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UniProt
- Q92611
抗原
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