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DIAPH3 抗体

This anti-DIAPH3 antibody is a 兔 多克隆 antibody detecting DIAPH3 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7468256
发货至: 中国

Quick Overview for DIAPH3 抗体 (ABIN7468256)

抗原

See all DIAPH3 抗体
DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

适用

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宿主

  • 49
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克隆类型

  • 51
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多克隆

标记

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This DIAPH3 antibody is un-conjugated

应用范围

  • 40
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    2.13 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

    别名

    diaphanous related formin 3

    背景

    Synonyms: diaphanous related formin 3 , AN , AUNA1 , DIA2 , DRF3 , NSDAN , diap3 , mDia2

    Background: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.

    分子量

    137 kDa

    基因ID

    81624

    UniProt

    Q9NSV4
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