ARID1B 抗体
Quick Overview for ARID1B 抗体 (ABIN7467972)
抗原
See all ARID1B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ARID1B. The exact sequence is proprietary.
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亚型
- IgG
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anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1364-1460) antibody
ARID1B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 400-650) antibodyARID1B 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (Internal Region) antibodyARID1B 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) antibodyARID1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1501-1600) antibodyARID1B 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (Internal Region) antibodyARID1B 适用: 人, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B) (AA 1371-1420) antibodyARID1B 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.32 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
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别名
- AT-rich interaction domain 1B
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背景
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Synonyms: AT-rich interaction domain 1B , 6A3-5 , BAF250B , BRIGHT , CSS1 , DAN15 , ELD/OSA1 , MRD12 , OSA2 , P250R
Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
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分子量
- 236 kDa
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基因ID
- 57492
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UniProt
- Q8NFD5
抗原
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