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WDYHV1 抗体

This anti-WDYHV1 antibody is a 兔 多克隆 antibody detecting WDYHV1 in IHC (p), ICC 和 IF. Suitable for 人.
产品编号 ABIN7467823
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for WDYHV1 抗体 (ABIN7467823)

抗原

See all WDYHV1 抗体
WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

适用

  • 12
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 12

克隆类型

  • 12
多克隆

标记

  • 8
  • 2
  • 1
  • 1
This WDYHV1 antibody is un-conjugated

应用范围

  • 7
  • 7
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human WDYHV1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.58 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

    别名

    WDYHV motif containing 1

    背景

    WDYHV motif containing 1 , C8orf32,Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

    分子量

    24 kDa

    基因ID

    55093

    UniProt

    Q96HA8
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