Deoxyuridine Triphosphatase (DUT) 抗体
Quick Overview for Deoxyuridine Triphosphatase (DUT) 抗体 (ABIN7467780)
抗原
See all Deoxyuridine Triphosphatase (DUT) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human DUT. The exact sequence is proprietary.
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亚型
- IgG
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anti-Deoxyuridine Triphosphatase (DUT) (AA 68-164) antibody
DUT 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 89-252) antibodyDUT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (Internal Region) antibodyVerified DUT 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 151-252) antibodyDUT 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) antibodyDUT 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (AA 1-252) antibodyDUT 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (C-Term) antibodyDUT 适用: 人, 大鼠, 小鼠, 犬, Bat, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyuridine Triphosphatase (DUT) (N-Term) antibodyDUT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.49 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Deoxyuridine Triphosphatase (DUT)
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别名
- deoxyuridine triphosphatase
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背景
- Deoxyuridine triphosphatase , dUTPase,This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq]
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分子量
- 27 kDa
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基因ID
- 1854
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UniProt
- P33316
抗原
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