NLRP2 抗体
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北京 101111
Quick Overview for NLRP2 抗体 (ABIN7467666)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human NALP2. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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别名
- NLR family pyrin domain containing 2
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背景
- NLR family pyrin domain containing 2 , CLR19.9 , NALP2 , NBS1 , PAN1 , PYPAF2,NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]
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分子量
- 121 kDa
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基因ID
- 55655
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UniProt
- Q9NX02
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途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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