RPE65 抗体
Quick Overview for RPE65 抗体 (ABIN7467624)
抗原
See all RPE65 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human RPE65. The exact sequence is proprietary.
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亚型
- IgG
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anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibody
RPE65 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 348-484) antibodyRPE65 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 274-533) antibodyRPE65 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (Internal Region) antibodyVerified RPE65 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人, 小鼠, Cow, Pig, 小鸡, 非洲爪蟾 WB, IF, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 401-8B11-3D9 unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 7B10 unconjugated Recombinant Antibody
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.36 mg/mL
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缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
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别名
- retinoid isomerohydrolase RPE65
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背景
- Retinoid isomerohydrolase RPE65 , BCO3 , LCA2 , RP20 , mRPE65 , p63 , rd12 , sRPE65,This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq]
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分子量
- 61 kDa
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基因ID
- 6121
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UniProt
- Q16518
抗原
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