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HIP1 抗体

This anti-HIP1 antibody is a 兔 多克隆 antibody detecting HIP1 in WB. Suitable for 人.
产品编号 ABIN7467610
发货至: 中国

Quick Overview for HIP1 抗体 (ABIN7467610)

抗原

See all HIP1 抗体
HIP1 (Huntingtin Interacting Protein 1 (HIP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human HIP1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , mouse brain , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.56 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    HIP1 (Huntingtin Interacting Protein 1 (HIP1))

    别名

    huntingtin interacting protein 1

    背景

    Huntingtin interacting protein 1 , HIP-I , ILWEQ , SHON , SHONbeta , SHONgamma,The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]

    分子量

    116 kDa

    基因ID

    3092

    UniProt

    O00291

    途径

    Positive Regulation of Endopeptidase Activity
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