FTO 抗体
Quick Overview for FTO 抗体 (ABIN7467605)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human FTO. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: U87-MG , SK-N-SH , IMR32 , SK-N-AS , 293T , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 2.05 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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别名
- FTO alpha-ketoglutarate dependent dioxygenase
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背景
- FTO alpha-ketoglutarate dependent dioxygenase , ALKBH9 , BMIQ14 , GDFD,The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death. [provided by RefSeq]
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分子量
- 58 kDa
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基因ID
- 79068
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UniProt
- Q9C0B1
抗原
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