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IVNS1ABP 抗体 (C-Term)

This anti-IVNS1ABP antibody is a 兔 多克隆 antibody detecting IVNS1ABP in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7467508
发货至: 中国

Quick Overview for IVNS1ABP 抗体 (C-Term) (ABIN7467508)

抗原

See all IVNS1ABP 抗体
IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

适用

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宿主

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克隆类型

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多克隆

标记

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This IVNS1ABP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: U87-MG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.57 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

    别名

    influenza virus NS1A binding protein

    物质类

    Influenza Protein

    背景

    Influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP,Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

    分子量

    72 kDa

    基因ID

    10625

    UniProt

    Q9Y6Y0

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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