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ITM2B 抗体

The 兔 多克隆 anti-ITM2B antibody (ABIN7467380) specifically detects ITM2B in WB, IHC (p), IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7467380
发货至: 中国
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Quick Overview for ITM2B 抗体 (ABIN7467380)

抗原

See all ITM2B 抗体
ITM2B (Integral Membrane Protein 2B (ITM2B))

适用

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宿主

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克隆类型

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多克隆

标记

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This ITM2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ITM2B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: rat brain , RT-4

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.81 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ITM2B (Integral Membrane Protein 2B (ITM2B))

    别名

    integral membrane protein 2B

    背景

    Integral membrane protein 2B , ABRI , BRI , BRI2 , BRICD2B , E25B , E3-16 , FBD , RDGCA , imBRI2,Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq]

    分子量

    30 kDa

    基因ID

    9445

    UniProt

    Q9Y287
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