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GIPR 抗体 (N-Term)

The 兔 多克隆 anti-GIPR antibody (ABIN7467374) specifically detects GIPR in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7467374
发货至: 中国
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Quick Overview for GIPR 抗体 (N-Term) (ABIN7467374)

抗原

See all GIPR 抗体
GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

适用

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宿主

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克隆类型

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多克隆

标记

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This GIPR antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    交叉反应

    大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GIPR. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.53 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

    别名

    gastric inhibitory polypeptide receptor

    背景

    Gastric inhibitory polypeptide receptor , PGQTL2,Gastric inhibitory polypeptide (GIP, MIM 137240), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM]

    分子量

    53 kDa

    基因ID

    2696

    UniProt

    P48546

    途径

    Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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