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PRR5 抗体

This anti-PRR5 antibody is a 兔 多克隆 antibody detecting PRR5 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7467337
发货至: 中国

Quick Overview for PRR5 抗体 (ABIN7467337)

抗原

See all PRR5 抗体
PRR5 (Proline Rich 5 (Renal) (PRR5))

适用

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宿主

  • 42

克隆类型

  • 42
多克隆

标记

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This PRR5 antibody is un-conjugated

应用范围

  • 34
  • 13
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Protor 1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Raji

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PRR5 (Proline Rich 5 (Renal) (PRR5))

    别名

    proline rich 5

    背景

    Proline rich 5 , FLJ20185k , PP610 , PROTOR-1 , PROTOR1,This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq]

    分子量

    43 kDa

    基因ID

    55615

    UniProt

    P85299

    途径

    PI3K-Akt Signaling
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