KRIT1 抗体
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北京 101111
Quick Overview for KRIT1 抗体 (ABIN7467269)
抗原
See all KRIT1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human KRIT1. The exact sequence is proprietary.
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亚型
- IgG
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anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 631-736) antibody
KRIT1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) antibodyKD Validated KRIT1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4350 unconjugated Recombinant Antibody
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 471-585) antibodyKRIT1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 637-736) antibodyKRIT1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-KRIT1, Ankyrin Repeat Containing (KRIT1) (AA 1-736), (N-Term) antibodyKRIT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Raji
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.74 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- KRIT1 (KRIT1, Ankyrin Repeat Containing (KRIT1))
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别名
- KRIT1 ankyrin repeat containing
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背景
- KRIT1 ankyrin repeat containing , CAM , CCM1,This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
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分子量
- 84 kDa
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基因ID
- 889
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UniProt
- O00522
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途径
- Cell RedoxHomeostasis
抗原
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