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Phospholamban 抗体 (pSer16)

This anti-Phospholamban antibody is a 兔 多克隆 antibody detecting Phospholamban in WB. Suitable for 人.
产品编号 ABIN7467195
发货至: 中国

Quick Overview for Phospholamban 抗体 (pSer16) (ABIN7467195)

抗原

See all Phospholamban (PLN) 抗体
Phospholamban (PLN)

适用

  • 86
  • 24
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宿主

  • 87
  • 3
  • 1

克隆类型

  • 86
  • 5
多克隆

标记

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This Phospholamban antibody is un-conjugated

应用范围

  • 37
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  • 22
  • 11
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    • 9
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    pSer16

    交叉反应

    小鼠, 兔

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Ser16 of human Phospholamban. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.97 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Phospholamban (PLN)

    别名

    phospholamban

    背景

    Phospholamban , CMD1P , CMH18 , PLB,The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]

    分子量

    6 kDa

    基因ID

    5350

    UniProt

    P26678

    途径

    Negative Regulation of Transporter Activity
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