SIRPA 抗体
Quick Overview for SIRPA 抗体 (ABIN7467146)
抗原
See all SIRPA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human SIRP alpha. The exact sequence is proprietary.
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亚型
- IgG
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 28-507) antibody
SIRPA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibodySIRPA 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2H7E2 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibodySIRPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibodySIRPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibodySIRPA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibodySIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibodySIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: Pig WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal BL1H7 unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.24 mg/mL
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缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
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别名
- signal regulatory protein alpha
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背景
- Signal regulatory protein alpha , BIT , CD172A , MFR , MYD-1 , P84 , PTPNS1 , SHPS1 , SIRP,The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq]
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分子量
- 55 kDa
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基因ID
- 140885
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UniProt
- P78324
抗原
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