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UBE2K 抗体

The 兔 多克隆 anti-UBE2K antibody is suitable to detect UBE2K in samples from 人. It has been validated for WB, IF 和 ICC.
产品编号 ABIN7466773
发货至: 中国
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Quick Overview for UBE2K 抗体 (ABIN7466773)

抗原

See all UBE2K 抗体
UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

适用

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宿主

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克隆类型

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多克隆

标记

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This UBE2K antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human HIP2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Mouse brain , HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

    别名

    ubiquitin conjugating enzyme E2 K

    背景

    Ubiquitin conjugating enzyme E2 K , E2-25K , HIP2 , HYPG , LIG , UBC1,The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

    分子量

    22 kDa

    基因ID

    3093

    UniProt

    P61086
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