Progesterone Receptor 抗体 (AA 1-101)
Quick Overview for Progesterone Receptor 抗体 (AA 1-101) (ABIN7466678)
抗原
See all Progesterone Receptor (PGR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-101
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特异性
- This antibody recognizes both Form A (94 kDa) and Form B (120 kDa) of the human progesterone receptor (PgR)
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交叉反应
- 人
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纯化方法
- Protein G purified
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免疫原
- 6-His fusion protein containing the region encoding amino acids 1-101 of the human progesterone receptor expressed in E. coli.
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亚型
- IgG2a
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应用备注
- WB: 1 - 5 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MCF7 lysate (GTX23871) & recombinant protein
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.2, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Progesterone Receptor (PGR)
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别名
- progesterone receptor
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背景
- Progesterone receptor , NR3C3 , PR,This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
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分子量
- 99 kDa
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基因ID
- 5241
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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