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Glutaminase 抗体 (C-Term)

The 小鼠 单克隆 anti-Glutaminase antibody (Clone GT3211) (ABIN7466666) specifically detects Glutaminase in WB, IF, ICC 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7466666
发货至: 中国
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Quick Overview for Glutaminase 抗体 (C-Term) (ABIN7466666)

抗原

See all Glutaminase (GLS) 抗体
Glutaminase (GLS)

适用

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宿主

  • 64
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小鼠

克隆类型

  • 44
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单克隆

标记

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This Glutaminase antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GT3211
  • 抗原表位

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    C-Term

    特异性

    Specific for GAC but not KGA isoform

    交叉反应

    人, 小鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Glutaminase C (GAC). The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MCF-7 , MDA-MB-231

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Glutaminase (GLS)

    别名

    glutaminase

    背景

    Glutaminase , AAD20 , CASGID , EIEE71 , GAC , GAM , GLS1 , KGA,Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]

    分子量

    65 kDa

    基因ID

    2744

    UniProt

    O94925

    途径

    Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect
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