Glutaminase 抗体 (C-Term)
Quick Overview for Glutaminase 抗体 (C-Term) (ABIN7466665)
抗原
See all Glutaminase (GLS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- C-Term
-
特异性
- Specific for GAC but not KGA isoform
-
交叉反应
- 人
-
纯化方法
- Affinity purified by Protein A.
-
免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Glutaminase C (GAC). The exact sequence is proprietary.
-
亚型
- IgG2b
-
-
-
-
应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: MCF-7 , MDA-MB-231
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, No Preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Glutaminase (GLS)
-
别名
- glutaminase
-
背景
- Glutaminase , AAD20 , CASGID , EIEE71 , GAC , GAM , GLS1 , KGA,Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM]
-
分子量
- 65 kDa
-
基因ID
- 2744
-
UniProt
- O94925
-
途径
- Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effect
抗原
-