RFWD3 抗体 (C-Term)
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- 抗原 See all RFWD3 抗体
- RFWD3 (Ring Finger and WD Repeat Domain 3 (RFWD3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFWD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human RFWD3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product RFWD3 Primary Antibody
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anti-Ring Finger and WD Repeat Domain 3 (RFWD3) (N-Term) antibody
RFWD3 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 3 (RFWD3) (Internal Region) antibodyRFWD3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 3 (RFWD3) (AA 651-749) antibodyRFWD3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B4 unconjugated
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MCF-7
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.96 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- RFWD3 (Ring Finger and WD Repeat Domain 3 (RFWD3))
- 别名
- ring finger and WD repeat domain 3 (RFWD3 产品)
- 别名
- RGD1305243 antibody, RFWD3 antibody, RNF201 antibody, BC027246 antibody, ring finger and WD repeat domain 3 antibody, Rfwd3 antibody, RFWD3 antibody
- 背景
- Ring finger and WD repeat domain 3 , FANCW , RNF201,E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53.
- 分子量
- 85 kDa
- 基因ID
- 55159
- UniProt
- Q6PCD5
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