DHCR7 抗体 (C-Term)
Quick Overview for DHCR7 抗体 (C-Term) (ABIN7466581)
抗原
See all DHCR7 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DHCR7. The exact sequence is proprietary.
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亚型
- IgG
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anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 437-463), (C-Term) antibody
DHCR7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17942 unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 1-475) antibodyDHCR7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 63-147) antibodyDHCR7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-7-Dehydrocholesterol Reductase (DHCR7) (AA 351-450) antibodyDHCR7 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Validation: KO/KD
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.86 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
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别名
- 7-dehydrocholesterol reductase
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背景
- 7-dehydrocholesterol reductase , SLOS,The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the penultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development (Moebius et al., 1998 [PubMed 9465114]).[supplied by OMIM]
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分子量
- 54 kDa
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基因ID
- 1717
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UniProt
- Q9UBM7
抗原
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