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RBM5 抗体 (C-Term)

This anti-RBM5 antibody is a 兔 多克隆 antibody detecting RBM5 in WB 和 IP. Suitable for 人.
产品编号 ABIN7466554
发货至: 中国

Quick Overview for RBM5 抗体 (C-Term) (ABIN7466554)

抗原

See all RBM5 抗体
RBM5 (RNA Binding Motif Protein 5 (RBM5))

适用

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宿主

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克隆类型

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  • 1
多克隆

标记

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This RBM5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human RBM5. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: K562 , THP-1

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    RBM5 (RNA Binding Motif Protein 5 (RBM5))

    别名

    RNA binding motif protein 5

    背景

    RNA binding motif protein 5 , G15 , H37 , LUCA-15 , LUCA15 , RMB5,Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

    分子量

    92 kDa

    基因ID

    10181

    UniProt

    P52756

    途径

    Ribonucleoprotein Complex Subunit Organization
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