TRRAP 抗体 (N-Term)
Quick Overview for TRRAP 抗体 (N-Term) (ABIN7466514)
抗原
See all TRRAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human TRRAP. The exact sequence is proprietary.
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亚型
- IgG
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anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 3015-3049), (C-Term) antibody
TRRAP 适用: 人 WB, IF 宿主: 兔 Polyclonal RB51386 unconjugated
anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 1703-1737), (C-Term) antibodyTRRAP 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51498 unconjugated
anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 3534-3770) antibodyTRRAP 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , NCI-H929 , 293T , A431 , HeLa , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
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别名
- transformation/transcription domain associated protein
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背景
- Transformation/transcription domain associated protein , PAF350/400 , PAF400 , STAF40 , TR-AP , Tra1,Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression.
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分子量
- 438 kDa
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基因ID
- 8295
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UniProt
- Q9Y4A5
抗原
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