ERI1 抗体
Quick Overview for ERI1 抗体 (ABIN7466500)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human ERI1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-66) antibodyERI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 1-345) antibodyERI1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (N-Term) antibodyERI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 51-150) antibodyERI1 适用: 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 231-280) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 29-78) antibodyERI1 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (C-Term) antibodyERI1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Exoribonuclease 1 (ERI1) (AA 2-249) antibodyERI1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , NCI-H929
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- exoribonuclease 1
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背景
- Exoribonuclease 1 , 3'HEXO , HEXO , THEX1,RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
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分子量
- 40 kDa
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基因ID
- 90459
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UniProt
- Q8IV48
抗原
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