Myosin IA 抗体
Quick Overview for Myosin IA 抗体 (ABIN7466482)
抗原
See all Myosin IA (MYO1A) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Myosin 1A. The exact sequence is proprietary.
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亚型
- IgG
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anti-Myosin IA (MYO1A) (AA 783-1043) antibody
MYO1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IA (MYO1A) (AA 781-1043) antibodyMYO1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin IA (MYO1A) (AA 944-1043) antibodyMYO1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myosin IA (MYO1A) (AA 276-304) antibodyMYO1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB19125 unconjugated
anti-Myosin IA (MYO1A) antibodyMYO1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , K562 , NCI-H929
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.68 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Myosin IA (MYO1A)
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别名
- myosin IA
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背景
- Myosin IA , BBMI , DFNA48 , MIHC , MYHL,The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein encoded by this gene envelops an actin core bundle that, by comparison, is static in structure. [provided by RefSeq]
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分子量
- 118 kDa
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基因ID
- 4640
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UniProt
- Q9UBC5
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途径
- Sensory Perception of Sound
抗原
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