PTTG1 抗体
Quick Overview for PTTG1 抗体 (ABIN7466291)
抗原
See all PTTG1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Full length human Securin Recombinant protein.
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亚型
- IgG
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anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-199) antibody
PTTG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (Internal Region) antibodyVerified PTTG1 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-202) antibodyPTTG1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 16-45), (N-Term) antibodyPTTG1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18596 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 93-113) antibodyPTTG1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 101-202) antibodyPTTG1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 2-202) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pituitary Tumor-Transforming 1 (PTTG1) (AA 1-100) antibodyPTTG1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1D9 unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: IMR32
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
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别名
- pituitary tumor-transforming 1
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背景
- Pituitary tumor-transforming 1 , EAP1 , HPTTG , PTTG , TUTR1,The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. [provided by RefSeq]
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分子量
- 22 kDa
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基因ID
- 9232
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UniProt
- O95997
抗原
-
