ADD2 抗体
Quick Overview for ADD2 抗体 (ABIN7466280)
抗原
See all ADD2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human beta Adducin. The exact sequence is proprietary.
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亚型
- IgG
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anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibody
ADD2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 401-500) antibodyADD2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 648-697) antibodyADD2 适用: 人, Cow, 马, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Middle Region) antibodyADD2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠, 兔 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HUVEC
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.57 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ADD2 (Adducin 2 (Beta) (ADD2))
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别名
- adducin 2
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背景
- Adducin 2 , ADDB,Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Various adducin beta mRNAs, alternatively spliced at 3'end and/or internally spliced and encoding different isoforms, have been described. The functions of all the different isoforms are not known. [provided by RefSeq]
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分子量
- 81 kDa
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基因ID
- 119
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UniProt
- P35612
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途径
- Regulation of Actin Filament Polymerization
抗原
-
