RNF185 抗体
Quick Overview for RNF185 抗体 (ABIN7466269)
抗原
See all RNF185 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human RNF185. The exact sequence is proprietary.
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亚型
- IgG
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anti-Ring Finger Protein 185 (RNF185) (AA 88-117) antibody
RNF185 适用: 人, 小鼠, Hamster WB, FACS 宿主: 兔 Polyclonal RB28159 unconjugated
anti-Ring Finger Protein 185 (RNF185) (AA 91-121), (Middle Region) antibodyRNF185 适用: 人, 小鼠, Hamster WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 185 (RNF185) antibodyRNF185 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 185 (RNF185) (AA 1-192) antibodyRNF185 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 185 (RNF185) (AA 74-123) antibodyRNF185 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 185 (RNF185) (AA 1-130) antibodyRNF185 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 185 (RNF185) (Middle Region) antibodyRNF185 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: human RNF185-transfected 293T
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.68 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RNF185 (Ring Finger Protein 185 (RNF185))
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别名
- ring finger protein 185
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背景
- Ring finger protein 185,E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693). Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036). Protects cells from ER stress-induced apoptosis (PubMed:27485036). Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521). Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).
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分子量
- 20 kDa
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基因ID
- 91445
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UniProt
- Q96GF1
抗原
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