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Coagulation Factor X 抗体

This anti-Coagulation Factor X antibody is a 小鼠 单克隆 antibody detecting Coagulation Factor X in WB, ICC 和 IF. Suitable for 人.
产品编号 ABIN7466218
发货至: 中国

Quick Overview for Coagulation Factor X 抗体 (ABIN7466218)

抗原

See all Coagulation Factor X (F10) 抗体
Coagulation Factor X (F10)

适用

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宿主

  • 59
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小鼠

克隆类型

  • 72
  • 15
单克隆

标记

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This Coagulation Factor X antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

GT268
  • 交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human Factor X. The exact sequence is proprietary.

    亚型

    IgG2b
  • 应用备注

    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: human F10-transfected 293T cells

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Coagulation Factor X (F10)

    别名

    coagulation factor X

    背景

    Coagulation factor X , FX , FXA,This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]

    分子量

    55 kDa

    基因ID

    2159

    UniProt

    P00742
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